Step-by-Step Guide: How to Survive to Wave 100 in Tower Defense Clash

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At the beginning of the infinite mode, it is recommended to ignore the “Attack” tab and instead immediately max out Cash/Wave and Coins/Wave. During the game, focus on increasing health, percentage defense, absolute defense, and thorn damage — this “turtle” style allows you to survive until wave 100.

As one experienced player writes:

“The simplest strategy is to ignore the attack tab on the run. Besides leveling the cash/wave and coins/wave at the start… just upgrade health, def %, def abs, and thorn damage during the run. That should get you pretty far…”

Other Reddit users emphasize the importance of knockback chance — the chance to knock back enemies — and another defensive trick.

The next important step is to prioritize the “Economy” button. Increasing your income will allow you to build key towers and buy upgrades in time.

Once you have earned enough resources, it is worth paying attention to cards. Users recommend enabling additional slots and composite cards, but only if you have truly useful cards. Don’t waste slots on useless cards.

The Enemy Balance card is also useful, as it increases the flow of enemies and multiplies income, giving you a resource boost on the wave. This is a great way to strengthen your economy, especially after waves 50-60.

Moving on to deep gameplay, aim to get the maximum number of lab slots (labs) — 5 labs provide access to powerful research. It’s worth opening them as early as possible.

At the same time, place a strong emphasis on maximum Thorn damage, which really helps in the later stages.

So, let’s summarize the algorithm:

  • At the start, secretly ignore the Attack tab and quickly pump up Cash/Wave and Coins/Wave.
  • During waves, improve your health, percentage and absolute defense, as well as thorn damage and knockback.
  • Pay attention to economic upgrades — they provide a steady flow of coins.
  • Only activate cards if they are useful; aim to open 4–5 slots.
  • Get the Enemy Balance card for more income.
  • As soon as you can, open laboratories and explore more actively.
  • Keep Thorn damage at the maximum level — it is critically important up to wave 100.

By sticking to this “turtle” strategy (buying defense, strengthening the economy, stable Thorn damage, and sensible use of cards and laboratories), many players pass wave 100 and beyond. These recommendations are confirmed by the experience of the top 1% of players on Reddit, and with this approach, the goal of “100 waves” becomes quite achievable.